Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 4/20 | 0.67 |
| ▸ | CCR2 | P41597 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | RORC | P51449 | 4/20 | 0.36 |
| ▸ | FABP4 | P15090 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16240536 | 0.87 | LDHA (0.68) | LDHACCR2CNR2RORC | |
| SCHEMBL12838 | 0.83 | LDHA (0.65) | LDHACCR2RORC | |
| SCHEMBL16240391 | 0.83 | LDHA (0.65) | LDHACCR2CNR2PPARGDAO | |
| SCHEMBL7624 | 0.80 | LDHA (1.00) | LDHACCR2DAO | |
| SCHEMBL16240296 | 0.80 | LDHA (0.71) | LDHACCR2 | |
| SCHEMBL8149 | 0.80 | LDHA (0.79) | LDHACCR2DAO | |
| SCHEMBL16240013 | 0.79 | LDHA (0.74) | LDHACCR2DAO | |
| SCHEMBL16240380 | 0.79 | LDHA (0.69) | LDHADAO | |
| SCHEMBL8347 | 0.75 | LDHA (0.66) | LDHACCR2RORCPPARGDAO | |
| SCHEMBL16240015 | 0.74 | LDHA (0.72) | LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343001-A1 | INDOLE DERIVATIVES INHIBITORS OF ENZYME LACTATE DEHYDROGENASE (LDH) | UNIVERSITA DI PISA (IT) | 2014-11-20 | — | — | US | claimed |
| US-20140343001-A1 | INDOLE DERIVATIVES INHIBITORS OF ENZYME LACTATE DEHYDROGENASE (LDH) | UNIVERSITA DI PISA (IT) | 2014-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343001-A1 | INDOLE DERIVATIVES INHIBITORS OF ENZYME LACTATE DEHYDROGENASE (LDH) | LDHA, LDHB, IDO1 | LDHA 1/4885CCR2 2549/4885CNR2 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.