Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16240668 | 1.00 | RAB9A (0.36) | RAB9AALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL14101130 | 0.84 | MAPT (0.42) | RAB9AALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL14337625 | 0.82 | MEN1 (0.41) | MAPTAKR1C3KMT2A | |
| SCHEMBL27891903 | 0.82 | KDM4E (0.56) | RAB9AALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL27908831 | 0.81 | APP (0.46) | RAB9AALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL18299800 | 0.80 | PDE2A (0.41) | RAB9ANPC1KMT2AGAA | |
| SCHEMBL18299803 | 0.80 | PDE2A (0.41) | RAB9ANPC1KMT2AGAA | |
| SCHEMBL18299799 | 0.80 | PDE2A (0.41) | RAB9ANPC1KMT2AGAA | |
| SCHEMBL23045576 | 0.80 | SMN1; SMN2 (0.44) | RAB9AALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL23045575 | 0.80 | SMN1; SMN2 (0.44) | RAB9AALDH1A1MAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233921-B2 | Potent poxvirus inhibitor | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-01-12 | — | — | US | disclosed |
| US-20140343114-A1 | Potent poxvirus inhibitor | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343114-A1 | Potent poxvirus inhibitor | MAVS, VAC14, GZMB | RAB9A 3228/4885ALDH1A1 3744/4885MAPT 3078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.