⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16241245 | 1.00 | — | — | |
| SCHEMBL16241246 | 1.00 | — | — | |
| SCHEMBL14879692 | 1.00 | — | — | |
| SCHEMBL16241006 | 1.00 | — | — | |
| SCHEMBL10207356 | 0.80 | CCR2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL895688 | 0.79 | CCR2 (0.30) | — | |
| SCHEMBL23853059 | 0.79 | LMNA (0.35) | — | |
| SCHEMBL18315773 | 0.78 | — | — | |
| SCHEMBL895141 | 0.77 | — | — | |
| SCHEMBL895142 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768491-B1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS INC (US) | 2016-12-21 | — | — | EP | disclosed |
| US-9266908-B2 | Inhibitors of arginase and their therapeutic applications | MARS, INCORPORATED (US) | 2016-02-23 | — | — | US | disclosed |
| US-20140343019-A1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS, INCORPORATED | 2014-11-20 | — | — | US | disclosed |