Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18196801 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPK1L3MBTL1SLC15A1ELANE | |
| SCHEMBL16245288 | 0.81 | SLC15A1 (0.44) | ALDH1A1MAPK1L3MBTL1SLC15A1KLK7 | |
| SCHEMBL22181023 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1HPGDTSHR | |
| SCHEMBL20966567 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1HPGDTSHR | |
| SCHEMBL16614382 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MAPK1L3MBTL1SLC15A1ELANE | |
| SCHEMBL18194647 | 0.77 | FKBP1A (0.33) | SMN1; SMN2 | |
| SCHEMBL18194636 | 0.77 | FKBP1A (0.33) | SMN1; SMN2 | |
| SCHEMBL20966572 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPK1L3MBTL1HPGDTSHR | |
| SCHEMBL1296194 | 0.76 | ABCB1 (0.42) | ALDH1A1MAPK1L3MBTL1SLC15A1BTN3A1 | |
| SCHEMBL1296191 | 0.76 | ABCB1 (0.42) | ALDH1A1MAPK1L3MBTL1SLC15A1BTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318862-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2016-11-03 | — | — | US | disclosed |
| WO-2015048268-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318862-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | DGKZ, DGKG, DNAJA3 | ALDH1A1 3849/4885MAPK1 1967/4885L3MBTL1 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.