Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320893 | 0.83 | CA1 (0.35) | CA1CA2PSMB8HDAC3HDAC1 | |
| SCHEMBL16245642 | 0.83 | CA1 (0.35) | CA1CA2PSMB8HDAC3HDAC1 | |
| SCHEMBL16935092 | 0.75 | ALDH1A1 (0.38) | SMN1; SMN2 | |
| SCHEMBL5347897 | 0.74 | CA1 (0.36) | CA1CA2PSMB8HDAC3HDAC1 | |
| SCHEMBL3175510 | 0.73 | CA1 (0.36) | CA1CA2PSMB8HDAC3HDAC1 | |
| SCHEMBL24049964 | 0.71 | KDM4E (0.49) | CA1CA2PSMB8HDAC3HDAC1 | |
| SCHEMBL11645385 | 0.69 | KDM4E (0.35) | TDP1 | |
| SCHEMBL4411003 | 0.69 | CA1 (0.36) | CA1CA2PSMB8HDAC3HDAC1 | |
| SCHEMBL31319651 | 0.69 | GABRA5 (0.36) | CA1CA2PSMB8HDAC3HDAC1 | |
| SCHEMBL29953477 | 0.69 | CA1 (0.33) | CA1CA2PSMB8HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9936701-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2018-04-10 | — | — | US | disclosed |
| US-9936701-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2018-04-10 | — | — | US | disclosed |
| US-9936701-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2018-04-10 | — | — | US | disclosed |
| EP-2993986-B1 | HERBICIDAL ISOXAZOLYL SUBSTITUTED PYRROLONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-10 | — | — | EP | disclosed |
| EP-2993986-A1 | HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2016-03-16 | — | — | EP | disclosed |
| US-20160066574-A1 | Herbicidal Compounds | SYNGENTA LIMITED (GB) | 2016-03-10 | — | — | US | disclosed |
| US-20160066574-A1 | Herbicidal Compounds | SYNGENTA LIMITED (GB) | 2016-03-10 | — | — | US | disclosed |
| US-20160066574-A1 | Herbicidal Compounds | SYNGENTA LIMITED (GB) | 2016-03-10 | — | — | US | disclosed |
| WO-2014180740-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160066574-A1 | Herbicidal Compounds | CBR3, DDT, RDX | CA1 2317/4885CA2 1448/4885PSMB8 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.