Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 6/20 | 0.39 |
| ▸ | CCNC | P24863 | 5/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20726690 | 0.83 | KDM4C (0.44) | DYRK1ANFATC1NCF1EGFRPIK3CA | |
| SCHEMBL134737 | 0.75 | NCF1 (0.58) | NCF1LOXL2KDM4EMAPTCYP1A2 | |
| SCHEMBL2008208 | 0.74 | CCNC (0.39) | DYRK1ANFATC1CDK8CCNCSLC22A12 | |
| SCHEMBL2879912 | 0.74 | NCF1 (0.57) | DYRK1ACDK8CCNCSLC22A12NCF1 | |
| SCHEMBL277030 | 0.74 | SLC22A12 (0.42) | DYRK1ANFATC1CDK8CCNCSLC22A12 | |
| SCHEMBL3147611 | 0.74 | CCR1 (0.46) | DYRK1ANFATC1CDK8CCNCSLC22A12 | |
| SCHEMBL277031 | 0.74 | EP300 (0.47) | DYRK1ANFATC1CDK8CCNCSLC22A12 | |
| SCHEMBL3147605 | 0.74 | CCNC (0.39) | DYRK1ANFATC1CDK8CCNCSLC22A12 | |
| SCHEMBL18574397 | 0.74 | CCNC (0.39) | DYRK1ANFATC1CDK8CCNCSLC22A12 | |
| SCHEMBL3577754 | 0.74 | AXL (0.47) | DYRK1ANFATC1CDK8CCNCSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067664-A1 | Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2024-02-29 | — | — | US | disclosed |
| EP-2998296-B1 | CYCLOALKYL ACID DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL APPLICATION THEREOF | Shanghai hengrui pharmaceutical co ltd (CN) | 2018-03-14 | — | — | EP | disclosed |
| EP-2998296-B1 | CYCLOALKYL ACID DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL APPLICATION THEREOF | Shanghai hengrui pharmaceutical co ltd (CN) | 2018-03-14 | — | — | EP | disclosed |
| US-9637484-B2 | Cycloalkyl acid derivative, preparation method thereof, and pharmaceutical application thereof | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) | 2017-05-02 | — | — | US | disclosed |
| US-9637484-B2 | Cycloalkyl acid derivative, preparation method thereof, and pharmaceutical application thereof | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) | 2017-05-02 | — | — | US | disclosed |
| US-9637484-B2 | Cycloalkyl acid derivative, preparation method thereof, and pharmaceutical application thereof | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) | 2017-05-02 | — | — | US | disclosed |
| US-20160108035-A1 | CYCLOALKYL ACID DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL APPLICATION THEREOF | Shanghai Hengrui Pharmaceutical Co., Lt.d (CN) | 2016-04-21 | — | — | US | disclosed |
| US-20160108035-A1 | CYCLOALKYL ACID DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL APPLICATION THEREOF | Shanghai Hengrui Pharmaceutical Co., Lt.d (CN) | 2016-04-21 | — | — | US | disclosed |
| US-20160108035-A1 | CYCLOALKYL ACID DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL APPLICATION THEREOF | Shanghai Hengrui Pharmaceutical Co., Lt.d (CN) | 2016-04-21 | — | — | US | disclosed |
| CN-104470898-B | Cycloalkyl formic acid analog derivative, its preparation method and in application pharmaceutically | SHANGHAI HENGRUI PHARMACEUTICAL CO.,LTD. (CN) | 2016-04-06 | — | — | CN | disclosed |
| EP-2998296-A1 | CYCLOALKYL ACID DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL APPLICATION THEREOF | Shanghai Hengrui Pharmaceutical Co. Ltd. (CN) | 2016-03-23 | — | — | EP | disclosed |
| EP-2998296-A1 | CYCLOALKYL ACID DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL APPLICATION THEREOF | Shanghai Hengrui Pharmaceutical Co. Ltd. (CN) | 2016-03-23 | — | — | EP | disclosed |
| CN-104470898-A | Cycloalkyl Acid Derivative, Preparation Method Thereof, And Pharmaceutical Application Thereof | SHANGHAI HENGRUI PHARM CO LTD | 2015-03-25 | — | — | CN | disclosed |
| WO-2014183555-A1 | CYCLOALKYL ACID DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL APPLICATION THEREOF | 上海恒瑞医药有限公司 (CN) | 2014-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108035-A1 | CYCLOALKYL ACID DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL APPLICATION THEREOF | UGP2, MPST, KYAT1 | DYRK1A 3823/4885NFATC1 3537/4885CDK8 3658/4885 |
| US-20240067664-A1 | Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device | CCND1, CCND2, DRD1 | DYRK1A 3498/4885NFATC1 4869/4885CDK8 1082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.