Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16248103 | 0.82 | ABL1 (0.38) | — | |
| SCHEMBL24244752 | 0.79 | TUBB4A (0.34) | — | |
| SCHEMBL609721 | 0.77 | CHRNA3 (0.38) | MCHR1 | |
| SCHEMBL610781 | 0.77 | MCHR1 (0.38) | MCHR1 | |
| SCHEMBL16248104 | 0.74 | SRD5A1 (0.33) | — | |
| SCHEMBL30786097 | 0.74 | HRH3 (0.51) | — | |
| SCHEMBL18951811 | 0.70 | TUBB4A (0.51) | MCHR1 | |
| SCHEMBL31371069 | 0.70 | SCN9A (0.30) | — | |
| SCHEMBL16248094 | 0.70 | PPARA (0.55) | — | |
| SCHEMBL12036828 | 0.68 | TUBB4A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603500-B1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | HOFFMANN LA ROCHE (CH) | 2014-11-19 | — | — | EP | disclosed |