Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611752 | 0.75 | DGAT1 (0.37) | KDM4EL3MBTL1 | |
| SCHEMBL610590 | 0.75 | KDM4E (0.40) | KDM4EKCNN4 | |
| SCHEMBL16248110 | 0.74 | KDM4E (0.33) | KDM4EL3MBTL1 | |
| SCHEMBL2931728 | 0.74 | PDE2A (0.34) | — | |
| SCHEMBL29695061 | 0.71 | SCN10A (0.33) | — | |
| SCHEMBL29108369 | 0.71 | SCN10A (0.33) | — | |
| SCHEMBL265343 | 0.70 | KMT2A (0.43) | KDM4EL3MBTL1 | |
| SCHEMBL19735731 | 0.68 | KDM4E (0.45) | KDM4EL3MBTL1 | |
| SCHEMBL15007 | 0.67 | KDM4E (0.61) | KDM4EL3MBTL1 | |
| SCHEMBL14903602 | 0.67 | THRA (0.43) | KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603500-B1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | HOFFMANN LA ROCHE (CH) | 2014-11-19 | — | — | EP | disclosed |