Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 10/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 10/20 | 0.49 |
| ▸ | GSK3A | P49840 | 3/20 | 0.45 |
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | CLK2 | P49760 | 2/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | STK3 | Q13188 | 2/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033424 | 0.81 | PSMD14 (0.62) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL30604782 | 0.80 | NR4A2 (0.56) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL2876594 | 0.80 | NR4A2 (0.56) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL1091417 | 0.80 | NCF1 (0.51) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL30880479 | 0.80 | NCF1 (0.51) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL7757756 | 0.80 | NCF1 (0.55) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL317787 | 0.80 | NCF1 (0.51) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL2876591 | 0.80 | NCF1 (0.51) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL29862680 | 0.80 | NCF1 (0.51) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL485347 | 0.80 | NCF1 (0.51) | NCF1PARP1NR1H2NR1H3GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8981086-B2 | Phosphine-ligated palladium sulfonate palladacycles | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-03-17 | — | — | US | disclosed |
| US-20150045570-A1 | PHOSPHINE-LIGATED PALLADIUM SULFONATE PALLADACYCLES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-02-12 | — | — | US | disclosed |
| US-8889857-B2 | Phosphine-ligated palladium sulfonate palladacycles | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045570-A1 | PHOSPHINE-LIGATED PALLADIUM SULFONATE PALLADACYCLES | PHOSPHO1, PDCD1, PDCD1LG2 | NCF1 4075/4885PARP1 613/4885NR1H2 4796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.