Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880479 | 1.00 | NCF1 (0.51) | NCF1KDM4ETDP1MEN1ALDH1A1 | |
| SCHEMBL4148183 | 0.86 | KDM4E (0.56) | KDM4ETDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL27991176 | 0.84 | KDM4E (0.50) | NCF1KDM4ETDP1MEN1ALDH1A1 | |
| SCHEMBL16248304 | 0.80 | NCF1 (0.52) | NCF1KDM4EMEN1KMT2APARP1 | |
| SCHEMBL9033424 | 0.80 | PSMD14 (0.62) | NCF1ALDH1A1PARP1NR1H2NR1H3 | |
| SCHEMBL6230425 | 0.79 | CCR1 (0.37) | NCF1KDM4ETDP1MEN1ALDH1A1 | |
| SCHEMBL29862680 | 0.79 | NCF1 (0.51) | NCF1KDM4ETDP1MEN1ALDH1A1 | |
| SCHEMBL2876594 | 0.79 | NR4A2 (0.56) | NCF1MEN1KMT2APARP1NR1H2 | |
| SCHEMBL7757756 | 0.79 | NCF1 (0.55) | NCF1MEN1KMT2APARP1NR1H2 | |
| SCHEMBL2876591 | 0.79 | NCF1 (0.51) | NCF1TDP1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| US-5897940-A | Ink jet transparencies | XEROX CORPORATION (US) | 1999-04-27 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| US-20250034139-A1 | AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY | PHARMA CINQ, LLC | 2025-01-30 | — | — | US | disclosed |
| US-12139483-B2 | Imidazoquinolyl compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity | PHARMA CINQ, LLC (US) | 2024-11-12 | — | — | US | disclosed |
| US-20240360131-A1 | BIARYL KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2024-10-31 | — | — | US | disclosed |
| US-12065437-B2 | Biaryl kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-20 | — | — | US | disclosed |
| US-20230086683-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-03-23 | — | — | US | disclosed |
| EP-4090657-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS | Platefuse, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |
| US-11351164-B2 | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-06-07 | — | — | US | disclosed |
| US-20210283123-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE | BRISTOL-MYERS SQUIBB COMPANY | 2021-09-16 | — | — | US | disclosed |
| US-4277607-A | Process for the preparation of 4-chloroquinolines | ROUSSEL UCLAF (FR) | 1981-07-07 | — | — | US | disclosed |
| EP-0001175-B1 | 4-AMINOQUINOLINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | JOHN WYETH & BROTHER LIMITED (GB) | 1981-04-15 | — | — | EP | disclosed |
| US-4259335-A | 1-Methyl-4-piperidinol esters of 4-quinolinylamino benzoates and antiinflammatory and analgesic compositions and methods employing them | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1981-03-31 | — | — | US | disclosed |
| US-4233305-A | ANALGESICS | ROUSSEL UCLAF (FR) | 1980-11-11 | — | — | US | disclosed |
| US-4160828-A | ANTIINFLAMMATORY AND ANTIRHEUMATIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-10 | — | — | US | disclosed |
| EP-0001175-A1 | 4-Aminoquinoline derivatives, a process for their preparation and pharmaceutical compositions containing them | JOHN WYETH & BROTHER LIMITED (GB) | 1979-03-21 | — | — | EP | disclosed |
| US-4091095-A | DIALKYLPHOSPHINYL-ALKYL ESTER OF A 2-(ARYL-AMINO) BENZOIC ACID, ANALGESICS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-05-23 | — | — | US | disclosed |
| US-4025629-A | HYPOTENSIVES, ANTIANXIETY | THE UPJOHN COMPANY (US) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11351164-B2 | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use | IDO1, IDO2, INMT | NCF1 2041/4885KDM4E 362/4885TDP1 1200/4885 |
| US-20210283123-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE | IDO1, IDO2, INMT | NCF1 2041/4885KDM4E 362/4885TDP1 1200/4885 |
| US-20230086683-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS | PLTP, PFKP, MPL | NCF1 1123/4885KDM4E 4505/4885TDP1 357/4885 |
| US-20250034139-A1 | AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY | AADAC, CASP1, AAAS | NCF1 384/4885KDM4E 1059/4885TDP1 2102/4885 |
| US-12065437-B2 | Biaryl kinase inhibitors | AAK1, NCK1, MARCKS | NCF1 1464/4885KDM4E 1500/4885TDP1 1573/4885 |
| US-12139483-B2 | Imidazoquinolyl compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity | NOD1, NLRP3, AADAC | NCF1 448/4885KDM4E 1620/4885TDP1 3015/4885 |
| US-20240360131-A1 | BIARYL KINASE INHIBITORS | AAK1, NCK1, MARCKS | NCF1 1464/4885KDM4E 1500/4885TDP1 1573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.