SCHEMBL16249155

SCHEMBL16249155

c1ccc(-c2nnc(-c3ccc(-c4cccc(N(c5ccccc5)c5ccccc5)c4)cc3)n2-c2cccc3ccccc23)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13133968 0.86 AKT1 (0.42)
SCHEMBL16249161 0.84 AKT1 (0.54)
SCHEMBL28949385 0.83 SMN1; SMN2 (0.51)
SCHEMBL29349692 0.83 SMN1; SMN2 (0.51)
SCHEMBL44765 0.83 SMN1; SMN2 (0.51)
SCHEMBL13805102 0.83 KDM4E (0.39)
SCHEMBL16249156 0.83 AKT1 (0.50)
SCHEMBL21965993 0.82 TDP1 (0.35)
SCHEMBL17464028 0.81 ALDH1A1 (0.33)
SCHEMBL16249154 0.79 THRB (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9054320-B2 1, 2, 4-triazole-based derivative, production process and use thereof, and organic electroluminescent device BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-06-09 US disclosed
US-9054320-B2 1, 2, 4-triazole-based derivative, production process and use thereof, and organic electroluminescent device BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-06-09 US disclosed
US-20140343293-A1 1, 2, 4-TRIAZOLE-BASED DERIVATIVE, PRODUCTION PROCESS AND USE THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE JiLin OLED Material Tech. Co., LTD. (CN) 2014-11-20 US disclosed
US-20140343293-A1 1, 2, 4-TRIAZOLE-BASED DERIVATIVE, PRODUCTION PROCESS AND USE THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE JiLin OLED Material Tech. Co., LTD. (CN) 2014-11-20 US disclosed