Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16249707 | 0.79 | GPR119 (0.46) | GPR119CYP2C9MEN1KMT2A | |
| SCHEMBL16249706 | 0.79 | GPR119 (0.46) | GPR119CYP2C9MEN1KMT2A | |
| SCHEMBL13060194 | 0.78 | GPR119 (0.52) | GPR119CYP2C9MEN1KMT2A | |
| SCHEMBL3486211 | 0.77 | GPR119 (0.60) | GPR119 | |
| SCHEMBL16422601 | 0.76 | MEN1 (0.67) | GPR119MEN1KMT2A | |
| SCHEMBL13132432 | 0.74 | GPR119 (0.50) | GPR119 | |
| SCHEMBL2775923 | 0.74 | GPR119 (0.56) | GPR119MEN1KMT2A | |
| SCHEMBL25391302 | 0.74 | MEN1 (0.67) | GPR119MEN1KMT2A | |
| SCHEMBL2792425 | 0.73 | MEN1 (0.60) | GPR119MEN1KMT2A | |
| SCHEMBL8406581 | 0.73 | GPR119 (0.52) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889684-B2 | Azaindolylphenyl sulfonamides as serine/threonine kinase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-18 | — | — | US | disclosed |
| US-8889684-B2 | Azaindolylphenyl sulfonamides as serine/threonine kinase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-18 | — | — | US | disclosed |