Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | ITGAL | P20701 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163483 | 1.00 | EPHX2 (0.53) | EPHX2ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL162523 | 1.00 | EPHX2 (0.53) | EPHX2ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL7135256 | 0.79 | ITGB2 (0.53) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL8402593 | 0.75 | SMN1; SMN2 (0.59) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL8402596 | 0.75 | SMN1; SMN2 (0.59) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL21693631 | 0.74 | NAMPT (0.46) | EPHX2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL24567560 | 0.73 | ITGB2 (0.48) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL9629888 | 0.73 | TRPA1 (0.48) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL8372493 | 0.72 | CES2 (0.61) | MEN1KMT2AJAK2JAK1TYK2 | |
| SCHEMBL19541944 | 0.72 | ITGB2 (0.47) | ITGB2ICAM1ITGALMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012029968-A1 | BENZAMIDE DERIVATIVE OR ITS SALT, AND INSECTICIDE, MITICIDE, NEMATICIDE OR SOIL PESTICIDE CONTAINING IT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2012-03-08 | — | — | WO | disclosed |