Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Cholesterol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.65 |
| ▸ | OSBP | P22059 | 4/20 | 0.82 |
| ▸ | RORC | P51449 | 3/20 | 0.82 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.82 |
| ▸ | USP2 | O75604 | 1/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.82 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.82 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.71 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.71 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.70 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.70 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.67 |
| ▸ | CRYAB | P02511 | 1/20 | 0.67 |
| ▸ | HMGCR | P04035 | 1/20 | 0.67 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.67 |
| ▸ | ITGAV | P06756 | 1/20 | 0.67 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.67 |
| ▸ | POLA1 | P09884 | 1/20 | 0.66 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cholesterol SCHEMBL29065777 | 1.00 | OSBP (0.82) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL28035647 | 1.00 | OSBP (0.82) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL1296896 | 0.93 | OSBP (0.82) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL29033213 | 0.93 | OSBP (0.82) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL27608874 | 0.93 | OSBP (0.91) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL27668883 | 0.92 | OSBP (0.93) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL1369602 | 0.92 | OSBP (0.93) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL29502101 | 0.92 | OSBP (0.93) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL27942138 | 0.92 | OSBP (0.96) | OSBPRORCOSBP2USP2LMNA | |
| Benzoic Acid SCHEMBL11147682 | 0.92 | OSBP (0.68) | OSBPRORCOSBP2USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852914-B | Thermochromic water-based ink containing cholesterol liquid crystal microcapsules and preparation method | 江苏泰格油墨有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-119044072-A | Liquid crystal sensor for detecting formaldehyde gas and preparation method thereof | 江南大学 | 2024-11-29 | — | — | CN | claimed |
| CN-118852914-A | Thermochromic water-based ink containing cholesterol liquid crystal microcapsules and preparation method | 江苏泰格油墨有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-117599728-A | Reaction kettle for vitamin production and production process | 新拓洋生物工程有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-117597118-A | Pharmaceutical composition for preventing or treating viral infection comprising as active ingredient a crude drug | QVET公司 | 2024-02-23 | — | — | CN | claimed |
| CN-115851087-B | Blue light diffusion prevention coating and application thereof | 广东粤港澳大湾区黄埔材料研究院 | 2023-10-10 | — | — | CN | claimed |
| CN-114908575-B | Liquid crystal ultraviolet-resistant finishing agent and application thereof to textiles | 江南大学 | 2023-06-16 | — | — | CN | claimed |
| CN-116206540-A | Multi-mode display layer made of up-conversion liquid crystal microcapsules and display application | 苏州科技大学 | 2023-06-02 | — | — | CN | claimed |
| CN-116157171-A | Medical device for visually indicating injection pressure of fluid | 贝朗梅尔松根股份公司 | 2023-05-23 | — | — | CN | claimed |
| CN-112323162-B | High-efficiency slow-release microcapsule cellulose fiber for wormwood | 广东欣和艾草科技有限公司 | 2023-05-05 | — | — | CN | claimed |
| EP-1647259-A1 | use for treatment of keratinic materials of compositions comprising electrophilic monomers and agents forming liquid crystals | L'OREAL (FR) | 2006-04-19 | — | — | EP | claimed |
| CN-1686156-A | Clamycin structurization emulsion composition | ZHANG WENFANG (CN) | 2005-10-26 | — | — | CN | claimed |
| US-20050112207-A1 | Pharmaceutical and diagnostic compositions containing nanoparticles useful for treating targeted tissues and cells | SHORR ROBERT (US) | 2005-05-26 | — | — | US | claimed |
| US-6328910-B1 | FOR IN SITU FORMATION OF AN POLYMERIC CYANOACRYLATE FILM ON MAMMALIAN SKIN WHICH CAN BE USED TO MONITOR THE SURFACE SKIN TEMPERATURE OF MAMMAL | MEDLOGIC GLOBAL CORPORATION | 2001-12-11 | — | — | US | claimed |
| WO-1997027360-A1 | PHASE SEPARATION APPARATUS | SCAPA GROUP PLC (GB) | 1997-07-31 | — | — | WO | claimed |
| EP-0467031-B1 | Medical-grade lipid-coated microbubbles, paramagnetic labelling thereof and their therapeutic use | CAVITATION CONTROL TECHNOLOGY (US) | 1997-07-30 | — | — | EP | claimed |
| US-5215680-A | Sterilization by filtering through polysulfone membrane the concentrated gas-in-liquid emulsion obtained from dissolving hydrophobic polypeptide-metal organic chelating ligand in fatty acid surfactant and shaking | CAVITATION-CONTROL TECHNOLOGY, INC. (US) | 1993-06-01 | — | — | US | claimed |
| EP-0467031-A2 | Medical-grade lipid-coated microbubbles, paramagnetic labelling thereof and their therapeutic use | CAVITATION-CONTROL TECHNOLOGY, INC. (US) | 1992-01-22 | — | — | EP | claimed |
| CN-1035145-A | FLUID CRYSTAL PRINTING WITH POLYURETHANL METHOD | WUHAN INST OF TEXTILE SCIENCE (CN) | 1989-08-30 | — | — | CN | claimed |
| US-4684479-A | Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures | CAVITATION-CONTROL TECHNOLOGY, INC. | 1987-08-04 | — | — | US | claimed |