SCHEMBL162547

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL163839	0.83	CA12 (0.43)	L3MBTL1RAB9AALDH1A1NPC1CYP1A2
	SCHEMBL162619	0.76	CYP1A2 (0.50)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL15205035	0.75	TSHR (0.50)	L3MBTL1ADRA1ARAB9AALDH1A1SMN1; SMN2
	SCHEMBL164560	0.74	GABRA1 (0.43)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL160032	0.73	TP53 (0.51)	ALDH1A1SMN1; SMN2CYP1A2MAPTLMNA
	SCHEMBL164373	0.73	GABRA1 (0.45)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL15204499	0.73	GABRA1 (0.40)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL165489	0.72	GABRA1 (0.44)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL162244	0.72	GABRA1 (0.50)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL162143	0.71	TSHR (0.51)	L3MBTL1ALDH1A1SMN1; SMN2CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.