Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28683257 | 0.86 | LMNA (0.52) | ALDH1A1TDP1CA2LMNAGPR84 | |
| SCHEMBL6860417 | 0.84 | CA2 (0.46) | ALDH1A1TDP1CA2CA1LMNA | |
| SCHEMBL2178204 | 0.81 | LMNA (0.44) | ALDH1A1CA2LMNAGPR84PRSS1 | |
| SCHEMBL5046988 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TDP1CA2CA1CYP3A4 | |
| SCHEMBL15401578 | 0.81 | MAPT (0.48) | TDP1CA2LMNAGPR84CYP3A4 | |
| SCHEMBL8513715 | 0.80 | CA2 (0.46) | ALDH1A1TDP1CA2CA1LMNA | |
| SCHEMBL8356601 | 0.79 | MAPT (0.52) | TDP1CA2LMNAGPR84CYP3A4 | |
| SCHEMBL10410671 | 0.79 | CA2 (0.50) | ALDH1A1TDP1CA2CA1LMNA | |
| SCHEMBL6600761 | 0.78 | LMNA (0.48) | ALDH1A1TDP1CA2CA1LMNA | |
| SCHEMBL6598059 | 0.78 | LMNA (0.48) | ALDH1A1TDP1CA2CA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032583-B1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2014-11-19 | — | — | EP | disclosed |