Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16255668 | 0.91 | ALDH1A1 (0.46) | MTORCYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL16255767 | 0.88 | ALDH1A1 (0.51) | KDM4ECYP1A2ALDH1A1LMNAMEN1 | |
| SCHEMBL12139602 | 0.87 | MTOR (0.46) | MTORALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL12141554 | 0.87 | MTOR (0.46) | MTORALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL16255699 | 0.86 | ALDH1A1 (0.52) | ALDH1A1LMNAMEN1TSHRKMT2A | |
| SCHEMBL16255781 | 0.83 | TSHR (0.65) | MTORCYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL12017807 | 0.83 | ADRB2 (0.55) | MTORALDH1A1MAPTPDE3BPDE3A | |
| SCHEMBL16255704 | 0.81 | KMT2A (0.52) | CYP1A2CYP2C19ALDH1A1LMNAMEN1 | |
| SCHEMBL27449929 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1LMNAMEN1TSHR | |
| SCHEMBL7923613 | 0.79 | MAPT (0.53) | ALDH1A1LMNAMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889706-B2 | Soluble mTOR complexes and modulators thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2014-11-18 | — | — | US | disclosed |