Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16256588 | 0.94 | CNR2 (0.38) | CNR2CYP3A4MAPTHPGDMEN1 | |
| SCHEMBL16256582 | 0.88 | CYP26A1 (0.36) | CNR2CYP3A4MAPTHPGDMEN1 | |
| SCHEMBL16256580 | 0.87 | CYP24A1 (0.36) | CNR2CYP3A4MAPTHPGDMEN1 | |
| SCHEMBL19071000 | 0.87 | DRD4 (0.33) | CNR2PIK3CACNR1XDH | |
| SCHEMBL16256584 | 0.82 | CYP26A1 (0.38) | CNR2ALDH1A1METAP1PIK3CACNR1 | |
| SCHEMBL19071509 | 0.81 | XDH (0.33) | PIK3CAXDH | |
| SCHEMBL16256579 | 0.81 | METAP1 (0.39) | CYP3A4MAPTHPGDMEN1USP2 | |
| SCHEMBL16256586 | 0.81 | CYP24A1 (0.37) | CNR2KMT2AMETAP1CNR1ACHE | |
| SCHEMBL19070317 | 0.80 | OPRL1 (0.33) | CNR2PIK3CACNR1ACHECYP26A1 | |
| SCHEMBL16256577 | 0.77 | ACHE (0.52) | CYP3A4MAPTHPGDMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |