Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 2/20 | 0.38 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16256582 | 0.94 | CYP26A1 (0.36) | CYP26A1CYP24A1CNR1CNR2METAP1 | |
| SCHEMBL16256586 | 0.88 | CYP24A1 (0.37) | CYP26A1CYP24A1CNR1CNR2METAP1 | |
| SCHEMBL16256588 | 0.88 | CNR2 (0.38) | CYP26A1CYP24A1CNR1CNR2METAP1 | |
| SCHEMBL19070718 | 0.87 | RIPK2 (0.36) | CYP26A1CNR1CNR2ACHEALDH1A1 | |
| SCHEMBL19071509 | 0.85 | XDH (0.33) | PIK3CA | |
| SCHEMBL16256580 | 0.82 | CYP24A1 (0.36) | CYP26A1CYP24A1CNR1CNR2METAP1 | |
| SCHEMBL16256581 | 0.82 | CNR2 (0.37) | CYP26A1CYP24A1CNR1CNR2METAP1 | |
| SCHEMBL16256578 | 0.81 | ACHE (0.41) | CYP26A1CYP24A1METAP1ACHEALDH1A1 | |
| SCHEMBL19071149 | 0.81 | DRD4 (0.33) | CYP26A1CNR1CNR2ALDH1A1CYP19A1 | |
| SCHEMBL16256576 | 0.76 | ACHE (0.56) | CYP26A1CYP24A1METAP1ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |