Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.40 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.37 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16256593 | 0.95 | KMT2A (0.40) | CYP24A1CYP27A1ACHECYP26A1METAP1 | |
| SCHEMBL16256600 | 0.85 | CYP24A1 (0.38) | CYP24A1CYP27A1ACHECYP26A1METAP1 | |
| SCHEMBL19071632 | 0.85 | MAOA (0.36) | KMT2AMEN1ALDH1A1HPGDPOLB | |
| SCHEMBL10196134 | 0.85 | MAOA (0.36) | KMT2AMEN1ALDH1A1HPGDPOLB | |
| SCHEMBL10196135 | 0.85 | LTB4R (0.35) | KMT2AMEN1HPGDMAPTHIF1A | |
| SCHEMBL19070696 | 0.85 | LTB4R (0.35) | KMT2AMEN1HPGDMAPTHIF1A | |
| SCHEMBL16256611 | 0.85 | ACHE (0.40) | CYP24A1ACHECYP26A1METAP1ATM | |
| SCHEMBL16256605 | 0.84 | CYP24A1 (0.38) | CYP24A1CYP27A1ACHECYP26A1METAP1 | |
| SCHEMBL10196022 | 0.84 | ANPEP (0.36) | CYP26A1CYP19A1 | |
| SCHEMBL19070623 | 0.84 | ANPEP (0.36) | CYP26A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |