Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16257635 | 0.91 | GLP1R (0.47) | GLP1RMEN1KMT2AFAAH | |
| SCHEMBL25651290 | 0.89 | GLP1R (0.43) | GLP1RFOLH1KDM4EMAPK1HIF1A | |
| SCHEMBL14683597 | 0.89 | GLP1R (0.43) | GLP1RFOLH1KDM4EMAPK1HIF1A | |
| SCHEMBL15259289 | 0.88 | GLP1R (0.46) | GLP1RMEN1KMT2AFAAH | |
| SCHEMBL25651306 | 0.88 | GLP1R (0.44) | GLP1RFOLH1KDM4EMAPK1HIF1A | |
| SCHEMBL1619320 | 0.87 | TSHR (0.43) | GLP1RKDM4EMEN1KMT2AFAAH | |
| SCHEMBL15002710 | 0.85 | GLP1R (0.44) | GLP1RFOLH1KDM4EMAPK1HIF1A | |
| SCHEMBL13880579 | 0.85 | GLP1R (0.43) | GLP1RMEN1KMT2AFAAH | |
| SCHEMBL26059894 | 0.85 | GLP1R (0.56) | GLP1RFOLH1KDM4E | |
| SCHEMBL17622202 | 0.85 | GLP1R (0.52) | GLP1RFOLH1MEN1KMT2AALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190879-A1 | DUAL-AGONIST COMPOUND FOR BOTH GLP-1 AND GIP RECEPTORS AND APPLICATION THEREOF | JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190879-A1 | DUAL-AGONIST COMPOUND FOR BOTH GLP-1 AND GIP RECEPTORS AND APPLICATION THEREOF | GLP1R, GIPR, GPR119 | GLP1R 1/4885FOLH1 692/4885KDM4E 4361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.