Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 8/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19375656 | 0.89 | GLP1R (0.44) | TSHRGLP1RFAAHALDH1A1HPGD | |
| SCHEMBL15259289 | 0.88 | GLP1R (0.46) | TSHRGLP1RFAAHMEN1KMT2A | |
| SCHEMBL25585043 | 0.88 | GLP1R (0.46) | TSHRGLP1RFAAHLMNANPC1 | |
| SCHEMBL22096266 | 0.88 | GLP1R (0.46) | TSHRGLP1RFAAHLMNANPC1 | |
| SCHEMBL26002137 | 0.87 | TSHR (0.41) | TSHRFAAHALDH1A1HPGDKDM4E | |
| SCHEMBL25651302 | 0.87 | GLP1R (0.45) | GLP1RFAAHKDM4EMEN1KMT2A | |
| SCHEMBL16257635 | 0.86 | GLP1R (0.47) | TSHRGLP1RFAAHALDH1A1NAMPT | |
| SCHEMBL16921333 | 0.81 | GLP1R (0.39) | GLP1RMEN1KMT2A | |
| SCHEMBL19375755 | 0.81 | GLP1R (0.49) | TSHRGLP1RLMNANPC1RAB9A | |
| SCHEMBL19375648 | 0.81 | GLP1R (0.49) | TSHRGLP1RLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088848-A1 | METHODS AND COMPOSITIONS FOR CONTROLLED POLYPEPTIDE SYNTHESIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-04-12 | — | — | US | disclosed |
| US-7968519-B2 | Amido-containing metal complexes; sonication; for self-assembling polypeptides; vesicles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-28 | — | — | US | disclosed |
| US-20080125581-A1 | Methods and compositions for controlled polypeptide synthesis | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2008-05-29 | — | — | US | disclosed |
| US-7329727-B2 | Methods and compositions for controlled polypeptide synthesis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088848-A1 | METHODS AND COMPOSITIONS FOR CONTROLLED POLYPEPTIDE SYNTHESIS | NGLY1, LNPEP, NPPA | TSHR 3552/4885GLP1R 675/4885FAAH 1903/4885 |
| US-20080125581-A1 | Methods and compositions for controlled polypeptide synthesis | NGLY1, LNPEP, NPPA | TSHR 3552/4885GLP1R 675/4885FAAH 1903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.