Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631294 | 0.82 | TSHR (0.48) | TSHRAKR1C3AKR1C2LMNAESR1 | |
| SCHEMBL7604782 | 0.82 | TSHR (0.48) | TSHRAKR1C3AKR1C2LMNAESR1 | |
| SCHEMBL8943569 | 0.81 | CES2 (0.39) | TSHRAKR1C3AKR1C2ALDH1A1ADRB1 | |
| SCHEMBL4062640 | 0.78 | TSHR (0.44) | TSHRLMNAESR1ESR2ALDH1A1 | |
| SCHEMBL30965001 | 0.78 | TSHR (0.44) | TSHRESR1ESR2ALDH1A1 | |
| SCHEMBL8251464 | 0.76 | UGT2B7 (0.45) | TSHRAKR1C3AKR1C2LMNATDP1 | |
| SCHEMBL12875453 | 0.75 | SLC6A2 (0.46) | TSHRLMNAALDH1A1ACHE | |
| SCHEMBL16216180 | 0.75 | PDE2A (0.42) | TSHRAKR1C3AKR1C2LMNATDP1 | |
| SCHEMBL14154807 | 0.75 | AKR1C3 (0.37) | TSHRAKR1C3AKR1C2LMNATDP1 | |
| SCHEMBL23429142 | 0.73 | S1PR1 (0.39) | ADRA2BS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2186794-B1 | MONOHALOGENATED PYRETHRIC ACID ALPHA-CYANO-4-FLUORO-3-PHENOXYBENZYL ESTER AND ITS PREPARATION METHOD AND USE | UNIV EAST CHINA NORMAL (CN) | 2014-11-26 | — | — | EP | disclosed |