Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.53 |
| ▸ | PPARD | Q03181 | 4/20 | 0.53 |
| ▸ | PPARA | Q07869 | 4/20 | 0.53 |
| ▸ | TERT | O14746 | 3/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | FABP4 | P15090 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TOP1 | P11387 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14770880 | 0.86 | ALDH1A1 (0.65) | PPARGPPARDPPARAMAPTBLM | |
| SCHEMBL23221964 | 0.77 | CES2 (0.54) | PPARGPPARDPPARAPTPN1HSD17B10 | |
| SCHEMBL23221963 | 0.77 | CES2 (0.54) | PPARGPPARDPPARAPTPN1HSD17B10 | |
| SCHEMBL1784609 | 0.75 | PPARG (0.61) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL247797 | 0.75 | PPARG (0.80) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL18720987 | 0.75 | PPARG (0.80) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL247796 | 0.75 | PPARG (0.80) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL1784610 | 0.75 | PPARG (0.61) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL11502529 | 0.75 | PPARG (0.61) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL371612 | 0.75 | PPARG (0.80) | PPARGPPARDPPARATERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2805726-A1 | Macrocyclic hepatitis C serine protease inhibitors | Enanta Pharmaceuticals, Inc. (US) | 2014-11-26 | — | — | EP | disclosed |