Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.61 |
| ▸ | PPARD | Q03181 | 4/20 | 0.61 |
| ▸ | PPARA | Q07869 | 4/20 | 0.61 |
| ▸ | TERT | O14746 | 3/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | BLM | P54132 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | FABP4 | P15090 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TOP1 | P11387 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11502529 | 1.00 | PPARG (0.61) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL1784609 | 1.00 | PPARG (0.61) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL1783654 | 0.98 | TERT (0.64) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL1783060 | 0.98 | TERT (0.64) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL1784621 | 0.98 | TERT (0.64) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL1783702 | 0.98 | TERT (0.64) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL1782209 | 0.98 | TERT (0.64) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL1783700 | 0.98 | TERT (0.64) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL1784194 | 0.98 | TERT (0.64) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL11705619 | 0.98 | TERT (0.64) | PPARGPPARDPPARATERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54019908-A | — | — | None | — | — | JP | disclosed |
| CN-112430453-B | Cooling liquid composition and cooling system | 丰田自动车株式会社 | 2022-06-14 | — | — | CN | disclosed |
| CN-112430453-A | Cooling liquid composition and cooling system | 丰田自动车株式会社 | 2021-03-02 | — | — | CN | disclosed |
| US-20170362533-A1 | ENAMINE AND/OR AMINAL FRAGRANCE PRECURSORS DERIVED FROM (E/Z)-9-HYDROXY-5,9-DI-METHYLDEC-4-ENAL | GIVAUDAN S.A. (CH) | 2017-12-21 | — | — | US | disclosed |
| US-9573872-B2 | Using mixtures of E/Z isomers to obtain quantitatively specific products by combining asymmetric hydrogenation and isomerization | DSM IP ASSETS B.V. (NL) | 2017-02-21 | — | — | US | disclosed |
| US-9458076-B2 | Using mixtures of E/Z isomers to obtain quantitatively specific products by combined asymmetric hydrogenations | DSM IP ASSETS B.V. (NL) | 2016-10-04 | — | — | US | disclosed |
| US-20160185702-A1 | USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINING ASYMMETRIC HYDROGENATION AND ISOMERIZATION | DSM IP ASSETS B.V. (NL) | 2016-06-30 | — | — | US | disclosed |
| US-20150321986-A1 | USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINED ASYMMETRIC HYDROGENATIONS | DSM IP ASSETS B.V. (NL) | 2015-11-12 | — | — | US | disclosed |
| US-9181163-B2 | Hydrogenation of ketones having at least a carbon-carbon double bond in the γ,δ-position | DSM IP ASSETS B.V. (NL) | 2015-11-10 | — | — | US | disclosed |
| US-20140249321-A1 | HYDROGENATION OF KETONES HAVING AT LEAST A CARBON-CARBON DOUBLE BOND IN THE y, -POSITION | DSM IP ASSETS B.V. (NL) | 2014-09-04 | — | — | US | disclosed |
| EP-2720996-A1 | HYDROGENATION OF KETONES HAVING AT LEAST A CARBON-CARBON DOUBLE BOND IN THE , -POSITION | DSM IP Assets B.V. (NL) | 2014-04-23 | — | — | EP | disclosed |
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| WO-2012171969-A1 | HYDROGENATION OF KETONES HAVING AT LEAST A CARBON-CARBON DOUBLE BOND IN THE γ, δ-POSITION | DSM IP ASSETS B.V. (NL) | 2012-12-20 | — | — | WO | disclosed |
| EP-2535323-A1 | Hydrogenation of ketones having at least a carbon-carbon double bond in the gamma-,delta-position | DSM IP Assets B.V. (NL) | 2012-12-19 | — | — | EP | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| EP-1687301-A1 | THIAEPOTHILONE FOR TREATING CANCEROUS DISEASES | LEIBNIZ-INSTITUT FÜR PFLANZENBIOCHEMIE (IPB) (DE) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005051947-A1 | THIAEPOTHILONE FOR TREATING CANCEROUS DISEASES | LEIBNIZ-INSTITUT FÜR PFLANZENBIOCHEMIE (IPB) (DE) | 2005-06-09 | — | — | WO | disclosed |
| US-4349626-A | Method of detecting Pseudomonas aeruginosa infections utilizing selected ketone and/or sulfur metabolites | THE MONELL CHEMICAL SENSES CENTER (US) | 1982-09-14 | — | — | US | disclosed |
| JP-S5419908-A | PREPARATION AND USE OF CIS-5-UNDECEN-2-ONE AND ITS NOVEL INTERMEDIATE | T HASEGAWA CO LTD | 1979-02-15 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362533-A1 | ENAMINE AND/OR AMINAL FRAGRANCE PRECURSORS DERIVED FROM (E/Z)-9-HYDROXY-5,9-DI-METHYLDEC-4-ENAL | HNMT, DRD5, H1-5 | PPARG 1844/4885PPARD 419/4885PPARA 972/4885 |
| US-20140249321-A1 | HYDROGENATION OF KETONES HAVING AT LEAST A CARBON-CARBON DOUBLE BOND IN THE y, -POSITION | VKORC1, VKORC1L1, CBR1 | PPARG 1167/4885PPARD 647/4885PPARA 1288/4885 |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | PPARG 1977/4885PPARD 2480/4885PPARA 1799/4885 |
| US-20150321986-A1 | USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINED ASYMMETRIC HYDROGENATIONS | EPHX2, HBZ, ELOVL5 | PPARG 292/4885PPARD 431/4885PPARA 271/4885 |
| US-20160185702-A1 | USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINING ASYMMETRIC HYDROGENATION AND ISOMERIZATION | EPHX2, ZDHHC2, GNE | PPARG 269/4885PPARD 423/4885PPARA 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.