Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD3 | Q15059 | 1/20 | 0.60 |
| ▸ | RB1 | P06400 | 7/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871473 | 0.95 | BRD3 (0.67) | BRD3RB1SIRT1SIRT2ADRA1D | |
| Hydrochloric Acid SCHEMBL4023634 | 0.94 | BRD3 (0.65) | BRD3RB1SIRT1SIRT2ADRA1D | |
| Methane SCHEMBL28731797 | 0.94 | BRD3 (0.65) | BRD3RB1SIRT1SIRT2ADRA1D | |
| SCHEMBL31497454 | 0.88 | SIRT1 (0.60) | BRD3RB1SIRT1SIRT2ADRA1D | |
| SCHEMBL8793149 | 0.88 | SIRT1 (0.60) | BRD3RB1SIRT1SIRT2ADRA1D | |
| Nazlinin SCHEMBL31662852 | 0.87 | HTR2A (0.51) | BRD3RB1SIRT1SIRT2ADRA1D | |
| SCHEMBL14930690 | 0.81 | BRD3 (0.60) | BRD3RB1SIRT1SIRT2ADRA1D | |
| SCHEMBL4153830 | 0.79 | CYP2D6 (0.58) | SIRT1SIRT2CYP2D6HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4138356 | 0.78 | CYP2D6 (0.57) | SIRT1SIRT2CYP2D6HSD17B10ALDH1A1 | |
| SCHEMBL8241408 | 0.78 | SIRT1 (0.92) | BRD3RB1SIRT1SIRT2MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254883-B1 | SUBSTITUTED INDOLE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2014-11-26 | — | — | EP | disclosed |