Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RB1 | P06400 | 4/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16258989 | 0.87 | BRD3 (0.60) | BRD3HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL1871473 | 0.85 | BRD3 (0.67) | BRD3HTR7CYP3A4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL4023634 | 0.84 | BRD3 (0.65) | BRD3HTR7CYP3A4CYP2D6CYP2C19 | |
| Methane SCHEMBL28731797 | 0.84 | BRD3 (0.65) | BRD3HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8793149 | 0.82 | SIRT1 (0.60) | BRD3HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL31497454 | 0.82 | SIRT1 (0.60) | BRD3HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL17839824 | 0.73 | HTR7 (0.65) | BRD3HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11845764 | 0.73 | HTR2A (0.81) | HTR2AHTR2CCYP2C19RB1NR2E1 | |
| SCHEMBL14930690 | 0.72 | BRD3 (0.60) | BRD3HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7074767 | 0.72 | HTR7 (0.55) | HTR2AHTR2CBRD3HTR7CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151874-A1 | INDOLE ALKALOID ANTIPLASMODIAL AGENTS AND PREPARATION THEREOF | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2025-07-17 | — | — | WO | disclosed |