Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MC4R | P32245 | 2/20 | 0.57 |
| ▸ | MC5R | P33032 | 2/20 | 0.57 |
| ▸ | MC3R | P41968 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16152208 | 1.00 | CHRM2 (0.62) | CHRM2MAOAMC4RMC5RMC3R | |
| Hydrochloric Acid SCHEMBL29778352 | 0.98 | CHRM2 (0.61) | CHRM2MAOAMC4RMC5RMC3R | |
| Hydrochloric Acid SCHEMBL29778300 | 0.98 | CHRM2 (0.61) | CHRM2MAOAMC4RMC5RMC3R | |
| SCHEMBL17770844 | 0.96 | CHRM2 (0.62) | CHRM2MAOAMC4RMC5RMC3R | |
| SCHEMBL16151774 | 0.92 | MC4R (0.66) | CHRM2MAOAMC4RMC5RMC3R | |
| SCHEMBL16136721 | 0.89 | MC4R (0.62) | CHRM2MAOAMC4RMC5RMC3R | |
| SCHEMBL16152234 | 0.89 | MC4R (0.62) | CHRM2MAOAMC4RMC5RMC3R | |
| SCHEMBL20127841 | 0.88 | CHRM2 (0.54) | CHRM2MAOAMC4RMC5RMC3R | |
| SCHEMBL18575582 | 0.88 | MC4R (0.63) | CHRM2MAOAMC4RMC5RMC3R | |
| SCHEMBL16152227 | 0.88 | CA12 (0.50) | CHRM2MAOAMC4RMC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10440955-B2 | Methods comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2019-10-15 | — | — | US | disclosed |
| US-20180125070-A1 | COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE | THE UNIVERSITY OF UTAH | 2018-05-10 | — | — | US | disclosed |
| US-20180125070-A1 | COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE | THE UNIVERSITY OF UTAH | 2018-05-10 | — | — | US | disclosed |
| US-9839219-B2 | Compositions comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2017-12-12 | — | — | US | disclosed |
| US-9839219-B2 | Compositions comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2017-12-12 | — | — | US | disclosed |
| US-20160330962-A1 | COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | CURZA GLOBAL, LLC | 2016-11-17 | — | — | US | disclosed |
| US-20160330962-A1 | COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | CURZA GLOBAL, LLC | 2016-11-17 | — | — | US | disclosed |
| US-9439433-B2 | Compositions and methods comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2016-09-13 | — | — | US | disclosed |
| US-9439433-B2 | Compositions and methods comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2016-09-13 | — | — | US | disclosed |
| US-9034927-B2 | Methods of use for compositions comprising a biocidal polyamine | CURZA GLOBAL, LLC (US) | 2015-05-19 | — | — | US | disclosed |
| US-20150038512-A1 | COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE | THE UNIVERSITY OF UTAH | 2015-02-05 | — | — | US | disclosed |
| US-20150038512-A1 | COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE | THE UNIVERSITY OF UTAH | 2015-02-05 | — | — | US | disclosed |
| WO-2014190096-A1 | COMPOSITIONS AND METHODS COMPRISING A POLYAMINE | CURZA GLOBAL, LLC (US) | 2014-11-27 | — | — | WO | disclosed |
| US-20140350017-A1 | METHODS OF USE FOR COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | THE UNIVERSITY OF UTAH (US) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350017-A1 | METHODS OF USE FOR COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | SRM, SMOX, SMS | CHRM2 3431/4885MAOA 113/4885MC4R 4854/4885 |
| US-20160330962-A1 | COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE | SRM, SMS, SMOX | CHRM2 3917/4885MAOA 116/4885MC4R 4796/4885 |
| US-10440955-B2 | Methods comprising a biocidal polyamine | SRM, SMOX, SMS | CHRM2 3986/4885MAOA 116/4885MC4R 4823/4885 |
| US-20180125070-A1 | COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE | SRM, SMOX, SMS | CHRM2 3947/4885MAOA 110/4885MC4R 4831/4885 |
| US-20150038512-A1 | COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE | SRM, SMOX, SMS | CHRM2 3947/4885MAOA 110/4885MC4R 4831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.