SCHEMBL16260415

SCHEMBL16260415

c1ccc(-c2cc(-c3ccccc3)nc(-n3c4ccccc4c4cc(-c5ccc(-n6c7ccccc7c7c8oc9ccccc9c8ccc76)cc5)ccc43)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.33
PLA2G4A P47712 1/20 0.33
KDM4E B2RXH2 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ATM Q13315 1/20 0.32
PTPRF P10586 3/20 0.31
PTPN2 P17706 3/20 0.31
PTPN1 P18031 3/20 0.31
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
TSHR P16473 1/20 0.30
BRCA1 P38398 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30
PTGER1 P34995 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16260407 0.94 PTGER1 (0.31) KDM4EL3MBTL1ALDH1A1MAPTHPGD
SCHEMBL16260412 0.93 MAPT (0.36) PLA2G2APLA2G4AKDM4EL3MBTL1ALDH1A1
SCHEMBL16260421 0.92 KDM4E (0.31) KDM4EL3MBTL1ALDH1A1MAPTHPGD
SCHEMBL16260414 0.91 KDM4E (0.33) PLA2G2APLA2G4AKDM4EL3MBTL1ALDH1A1
SCHEMBL19928016 0.91 KMT2A (0.33) PLA2G2APLA2G4AKDM4EL3MBTL1ALDH1A1
SCHEMBL17246156 0.90 ALDH1A1 (0.34) KDM4EL3MBTL1ALDH1A1MAPTHPGD
SCHEMBL16260413 0.90 KDM4E (0.32) PLA2G2APLA2G4AKDM4EL3MBTL1ALDH1A1
SCHEMBL24676194 0.89 KDM4E (0.40) PLA2G2APLA2G4AKDM4EL3MBTL1ALDH1A1
SCHEMBL24676062 0.89 KDM4E (0.40) PLA2G2APLA2G4AKDM4EL3MBTL1ALDH1A1
SCHEMBL18120460 0.88 PLA2G2A (0.35) PLA2G2APLA2G4AKDM4EL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140346483-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING ELEMENT CHEIL INDUSTRIES, INC. (KR) 2014-11-27 US disclosed
US-20140346483-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING ELEMENT CHEIL INDUSTRIES, INC. (KR) 2014-11-27 US disclosed