SCHEMBL19928016

SCHEMBL19928016

c1ccc(-c2cc(-c3ccccc3)nc(-n3c4ccccc4c4c5oc6ccccc6c5ccc43)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.33
MAPT P10636 6/20 0.33
MEN1 O00255 6/20 0.33
HSD17B10 Q99714 6/20 0.33
CYP3A4 P08684 4/20 0.33
KDM4E B2RXH2 4/20 0.33
HPGD P15428 3/20 0.33
GAA P10253 2/20 0.33
PKM P14618 2/20 0.33
RECQL P46063 2/20 0.33
ALPI P09923 1/20 0.33
CASP3 P42574 1/20 0.33
BLM P54132 1/20 0.33
CASP7 P55210 1/20 0.33
CASP6 P55212 1/20 0.33
MCL1 Q07820 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16260421 0.93 KDM4E (0.31) MAPTKDM4EHPGDL3MBTL1ALDH1A1
SCHEMBL16260407 0.93 PTGER1 (0.31) MAPTKDM4EHPGDL3MBTL1PTGER1
SCHEMBL16810960 0.91 ALOX5 (0.38) KMT2AMAPTMEN1HSD17B10CYP3A4
SCHEMBL16260415 0.91 PLA2G2A (0.33) KMT2AMAPTMEN1HSD17B10KDM4E
SCHEMBL16811044 0.91 ALOX5 (0.40) KMT2AMAPTMEN1HSD17B10CYP3A4
SCHEMBL18593799 0.90 MAPT (0.43) KMT2AMAPTMEN1HSD17B10CYP3A4
SCHEMBL20791958 0.90 ALOX5 (0.34) KMT2AMAPTMEN1HSD17B10CYP3A4
SCHEMBL16811130 0.90 ALOX5 (0.37) KMT2AMAPTMEN1HSD17B10CYP3A4
SCHEMBL9890028 0.89 MAPT (0.32) KMT2AMAPTMEN1HSD17B10CYP3A4
SCHEMBL16811521 0.89 ALOX5 (0.36) PLA2G2APLA2G4AALOX5PIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11753426-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and organic light-emitting apparatus including the organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-12 US disclosed
US-11753426-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and organic light-emitting apparatus including the organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-12 US disclosed
US-20190263849-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND ORGANIC LIGHT-EMITTING APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-29 US disclosed
US-9911924-B2 Material for organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed
US-9911924-B2 Material for organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190263849-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND ORGANIC LIGHT-EMITTING APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, L3MBTL1, MSL1 KMT2A 1255/4885MAPT 867/4885MEN1 29/4885
US-11753426-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and organic light-emitting apparatus including the organic light-emitting device L1CAM, L3MBTL1, MSL1 KMT2A 1255/4885MAPT 867/4885MEN1 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.