Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16270210 | 0.93 | L3MBTL1 (0.50) | KMT2AGAAALDH1A1LMNAMAPT | |
| SCHEMBL27142282 | 0.91 | KMT2A (0.59) | KMT2APRSS1PRSS2PRSS3GAA | |
| SCHEMBL28724455 | 0.91 | KMT2A (0.59) | KMT2APRSS1PRSS2PRSS3GAA | |
| SCHEMBL28723326 | 0.91 | KMT2A (0.59) | KMT2APRSS1PRSS2PRSS3GAA | |
| SCHEMBL6868914 | 0.91 | KMT2A (0.59) | KMT2APRSS1PRSS2PRSS3GAA | |
| SCHEMBL23272065 | 0.91 | KMT2A (0.59) | KMT2APRSS1PRSS2PRSS3GAA | |
| SCHEMBL13292705 | 0.91 | KMT2A (0.59) | KMT2APRSS1PRSS2PRSS3GAA | |
| SCHEMBL6866899 | 0.89 | KMT2A (0.61) | KMT2APRSS1PRSS2PRSS3GAA | |
| SCHEMBL11956809 | 0.88 | GAA (0.47) | KMT2AGAAHDAC1HDAC2HDAC3 | |
| SCHEMBL10301416 | 0.86 | KMT2A (0.47) | KMT2APRSS1PRSS2PRSS3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160023997-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | BEZWADA BIOMEDICAL LLC (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160023997-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | BEZWADA BIOMEDICAL LLC (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160023997-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | BEZWADA BIOMEDICAL LLC (US) | 2016-01-28 | — | — | US | disclosed |
| US-20150080301-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | BEZWADA BIOMEDICAL LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-20150080301-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | BEZWADA BIOMEDICAL LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-20150080301-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | BEZWADA BIOMEDICAL LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-8901347-B1 | Absorbable polyurethanes and methods of use thereof | BEZWADA BIOMEDICAL, LLC (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901347-B1 | Absorbable polyurethanes and methods of use thereof | BEZWADA BIOMEDICAL, LLC (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901347-B1 | Absorbable polyurethanes and methods of use thereof | BEZWADA BIOMEDICAL, LLC (US) | 2014-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080301-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | HPGDS, ITGAM, P4HTM | KMT2A 4067/4885PRSS1 2171/4885PRSS2 1850/4885 |
| US-20160023997-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | HPGDS, ITGAM, P4HTM | KMT2A 4067/4885PRSS1 2171/4885PRSS2 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.