SCHEMBL162631

SCHEMBL162631

COC(=O)c1ccc(C(=O)OC)c(O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.71
CA1 P00915 5/20 0.71
CA2 P00918 5/20 0.71
CA7 P43166 5/20 0.71
CA9 Q16790 5/20 0.71
CA14 Q9ULX7 5/20 0.71
XDH P47989 2/20 0.71
PDK2 Q15119 1/20 0.69
PDK4 Q16654 1/20 0.69
KDM4E B2RXH2 8/20 0.65
ALDH1A1 P00352 6/20 0.65
GAA P10253 3/20 0.65
HSD17B10 Q99714 3/20 0.65
MAPT P10636 3/20 0.65
HPGD P15428 3/20 0.65
GLA P06280 1/20 0.65
CASP1 P29466 1/20 0.65
CASP7 P55210 1/20 0.65
ATM Q13315 1/20 0.65
LMNA P02545 4/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29501115 1.00 CA12 (0.71) CA12CA1CA2CA7CA9
SCHEMBL10564137 0.98 CA12 (0.69) CA12CA1CA2CA7CA9
SCHEMBL1483249 0.89 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL5917807 0.89 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL9122345 0.89 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL5082071 0.89 SMN1; SMN2 (0.65) CA12CA1CA2CA7CA9
SCHEMBL14898202 0.87 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL20414588 0.87 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL4209898 0.86 CA12 (0.68) CA12CA1CA2CA7CA9
SCHEMBL4209892 0.86 CA12 (0.66) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 570 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12472271-B2 HDAC6 inhibitors and imaging agents THE GENERAL HOSPITAL CORPORATION (US) 2025-11-18 US claimed
CN-118420892-B High-temperature-resistant optical film material for polaroid and preparation method thereof 潍坊恒彩数码影像材料有限公司 2024-10-18 CN claimed
CN-118420892-A High-temperature-resistant optical film material for polaroid and preparation method thereof 潍坊恒彩数码影像材料有限公司 2024-08-02 CN claimed
US-20240148915-A1 HDAC6 Inhibitors and Imaging Agents THE GENERAL HOSPITAL CORPORATION 2024-05-09 US claimed
CN-106432722-B High-performance fiber and preparation method thereof 华东理工大学 2018-11-16 CN claimed
CN-106432722-A High-performance fiber and preparation method thereof 华东理工大学 2017-02-22 CN claimed
EP-1344765-B1 PROCESS FOR PRODUCING A DIMETHYL TEREPHTHALATE COMPOSITION TEIJIN LTD (JP) 2014-07-30 EP claimed
US-8293928-B2 Fluorinated 4-oxo-chroman-7-carboxylates E I DU PONT DE NEMOURS AND COMPANY (US) 2012-10-23 US claimed
US-20110213166-A1 FLUORINATED 4-OXO-CHROMAN-7-CARBOXYLATES E.I. DU PONT DE NEMOURS AND COMPANY (DE) 2011-09-01 US claimed
WO-2011028766-A2 FLUORINATED 4-OXO-CHROMAN-CARBOXYLATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-10 WO claimed
CN-1483015-A dimethyl terephthalate composition and process for producing the same ������������ʽ���� 2004-03-17 CN claimed
EP-1344765-A1 DIMETHYL TEREPHTHALATE COMPOSITION AND PROCESS FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 2003-09-17 EP claimed
EP-0708792-A1 PREPARATION OF BRANCHED POLYETHYLENE TEREPHTHALATE EASTMAN CHEMICAL COMPANY (US) 1996-05-01 EP claimed
WO-1995002623-A1 PREPARATION OF BRANCHED POLYETHYLENE TEREPHTHALATE EASTMAN CHEMICAL COMPANY (US) 1995-01-26 WO claimed
US-5376735-A Preparation of branched polyethylene terephthalate EASTMAN CHEMICAL COMPANY (US) 1994-12-27 US claimed
US-4833023-A CONTAINING SOILD PLASTICIZER MITSUBISHI PAPER MILLS, LTD. (JP) 1989-05-23 US claimed
US-4745026-A FINE PARTICLE SOLID PLASTICIZER MITSUBISHI PAPER MILLS, LTD. (JP) 1988-05-17 US claimed
EP-0132717-B1 HEAT-SENSITIVE RECORD MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-04-22 EP claimed
US-4540999-A HYDROXYPHTHALATE, CHROMOGEN KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1985-09-10 US claimed
EP-0132717-A1 Heat-sensitive record material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-02-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110213166-A1 FLUORINATED 4-OXO-CHROMAN-7-CARBOXYLATES PFAS, RNGTT, RCC1 CA12 3129/4885CA1 3212/4885CA2 1628/4885
US-20240148915-A1 HDAC6 Inhibitors and Imaging Agents HDAC1, HDAC6, HDAC11 CA12 640/4885CA1 377/4885CA2 2233/4885
US-12472271-B2 HDAC6 inhibitors and imaging agents HDAC1, HDAC6, HDAC11 CA12 640/4885CA1 377/4885CA2 2233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.