Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16263374 | 1.00 | PLA2G2C (0.42) | PLA2G2CEPHX2CES2CES1CYP2C9 | |
| SCHEMBL16263367 | 0.89 | PLA2G2C (0.33) | PLA2G2CEPHX2 | |
| SCHEMBL7560983 | 0.82 | CES2 (0.46) | PLA2G2CCES2CES1HSD17B10 | |
| SCHEMBL7561382 | 0.82 | CES2 (0.46) | PLA2G2CCES2CES1HSD17B10 | |
| SCHEMBL7563633 | 0.82 | CES2 (0.46) | PLA2G2CCES2CES1HSD17B10 | |
| SCHEMBL17207738 | 0.79 | HTT (0.34) | — | |
| SCHEMBL7261876 | 0.78 | CES2 (0.37) | CES2CES1TSHRHSD17B10 | |
| SCHEMBL7563208 | 0.74 | CES2 (0.41) | PLA2G2CCES2CES1TSHRHSD17B10 | |
| SCHEMBL18992794 | 0.73 | TSHR (0.48) | PLA2G2CEPHX2CES2CES1TSHR | |
| SCHEMBL7563122 | 0.71 | DGAT1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140350181-A1 | HYDRO-FLUOROCOMPOUNDS | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350181-A1 | HYDRO-FLUOROCOMPOUNDS | AFF4, AFF1, HAX1 | PLA2G2C 1878/4885EPHX2 248/4885CES2 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.