Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | BRS3 | P32247 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950272 | 0.81 | PKM (0.32) | PKMKDM4EPOLBRECQLPMP22 | |
| SCHEMBL6948633 | 0.74 | — | — | |
| SCHEMBL9425091 | 0.72 | BRS3 (0.38) | PKMBRS3KDM4EPOLBRECQL | |
| SCHEMBL810902 | 0.69 | BRS3 (0.47) | BRS3POLBNPSR1 | |
| SCHEMBL14037799 | 0.67 | — | — | |
| SCHEMBL7688678 | 0.67 | HPGDS (0.50) | BRS3 | |
| SCHEMBL278 | 0.67 | GPR84 (0.44) | PKMBRS3 | |
| SCHEMBL5791952 | 0.67 | MAPK1 (0.31) | PKMBRS3 | |
| SCHEMBL11087844 | 0.67 | — | — | |
| SCHEMBL13187443 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2537831-B1 | IMIDAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2014-12-03 | — | — | EP | claimed |
| EP-2537831-B1 | IMIDAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2014-12-03 | — | — | EP | disclosed |