Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16262380 | 0.91 | KMT2A (0.49) | KMT2AHDAC1HDAC2PRSS1PRSS2 | |
| SCHEMBL16270246 | 0.88 | HDAC1 (0.38) | HDAC1HDAC2MMP3HDAC3HDAC4 | |
| SCHEMBL15726604 | 0.87 | KMT2A (0.44) | KMT2APRSS1PRSS2PRSS3ESR1 | |
| SCHEMBL16270209 | 0.83 | L3MBTL1 (0.47) | KMT2AHDAC1HDAC2MMP3ESR1 | |
| SCHEMBL31338732 | 0.82 | GAA (0.41) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL14802443 | 0.82 | PRSS1 (0.37) | KMT2APRSS1PRSS2PRSS3ESR1 | |
| SCHEMBL15726640 | 0.81 | KMT2A (0.38) | KMT2APRSS1PRSS2PRSS3GAA | |
| SCHEMBL9964592 | 0.80 | CYP3A4 (0.39) | GAASMN1; SMN2CYP1A2 | |
| SCHEMBL15726670 | 0.80 | CYP3A4 (0.35) | KMT2AGAA | |
| SCHEMBL11956764 | 0.80 | CYP3A4 (0.37) | KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160023997-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | BEZWADA BIOMEDICAL LLC (US) | 2016-01-28 | — | — | US | disclosed |
| US-20150080301-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | BEZWADA BIOMEDICAL LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-8901347-B1 | Absorbable polyurethanes and methods of use thereof | BEZWADA BIOMEDICAL, LLC (US) | 2014-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080301-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | HPGDS, ITGAM, P4HTM | KMT2A 4067/4885HDAC1 2694/4885HDAC2 3131/4885 |
| US-20160023997-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | HPGDS, ITGAM, P4HTM | KMT2A 4067/4885HDAC1 2694/4885HDAC2 3131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.