Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 9/20 | 0.39 |
| ▸ | ACR | P10323 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.38 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.38 |
| ▸ | HPN | P05981 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | SLC47A2 | Q86VL8 | 2/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12152614 | 0.89 | PRSS1 (0.41) | PRSS1CYP1A2CYP2D6SLC6A2PRSS2 | |
| SCHEMBL15708348 | 0.89 | CYP3A4 (0.42) | PRSS1F2KMT2ACYP1A2PRSS2 | |
| SCHEMBL16574509 | 0.88 | SERPINE1 (0.42) | PRSS1CYP1A2CYP2D6SLC6A2PRSS2 | |
| SCHEMBL16270514 | 0.88 | PRSS1 (0.43) | PRSS1ACRF2KMT2ASLC22A2 | |
| SCHEMBL9420499 | 0.85 | SERPINE1 (0.49) | PRSS1CYP1A2CYP2D6SLC6A2PRSS2 | |
| SCHEMBL9420514 | 0.85 | SERPINE1 (0.49) | PRSS1CYP1A2CYP2D6SLC6A2PRSS2 | |
| SCHEMBL9420474 | 0.85 | SERPINE1 (0.49) | PRSS1CYP1A2CYP2D6SLC6A2PRSS2 | |
| SCHEMBL11956787 | 0.84 | PRSS1 (0.34) | PRSS1ACRKMT2ACYP1A2CYP2D6 | |
| SCHEMBL11925961 | 0.84 | TMPRSS15 (0.35) | PRSS1PRSS2PRSS3CTSL | |
| SCHEMBL16270525 | 0.84 | GAA (0.39) | PRSS1ACRMAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160023997-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | BEZWADA BIOMEDICAL LLC (US) | 2016-01-28 | — | — | US | disclosed |
| US-20150080301-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | BEZWADA BIOMEDICAL LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-8901347-B1 | Absorbable polyurethanes and methods of use thereof | BEZWADA BIOMEDICAL, LLC (US) | 2014-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080301-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | HPGDS, ITGAM, P4HTM | PRSS1 2171/4885ACR 4390/4885F2 33/4885 |
| US-20160023997-A1 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF | HPGDS, ITGAM, P4HTM | PRSS1 2171/4885ACR 4390/4885F2 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.