Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CD74 | P04233 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL219360 | 0.86 | NPC1 (0.57) | ALDH1A1MEN1MAPTKMT2ANR4A2 | |
| SCHEMBL216976 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MEN1MAPTKMT2ANR4A2 | |
| SCHEMBL219537 | 0.82 | NR4A2 (0.49) | ALDH1A1MEN1KMT2ANR4A2L3MBTL1 | |
| SCHEMBL219242 | 0.81 | ALDH1A3 (0.54) | ALDH1A1MEN1KMT2ANR4A2L3MBTL1 | |
| SCHEMBL220106 | 0.80 | ABL1 (0.45) | ALDH1A1MEN1MAPTKMT2ANR4A2 | |
| SCHEMBL219985 | 0.80 | NR4A2 (0.40) | ALDH1A1MEN1MAPTKMT2ANR4A2 | |
| SCHEMBL219685 | 0.80 | NR4A2 (0.40) | ALDH1A1MEN1KMT2ANR4A2CYP2C9 | |
| SCHEMBL219842 | 0.80 | NR4A2 (0.45) | ALDH1A1MEN1MAPTKMT2ANR4A2 | |
| SCHEMBL218784 | 0.79 | IRAK4 (0.41) | ALDH1A1MEN1MAPTKMT2ANR4A2 | |
| SCHEMBL2735668 | 0.78 | L3MBTL1 (0.42) | ALDH1A1MEN1MAPTKMT2ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262804-B1 | POLYSUBSTITUTED DERIVATIVES OF 6-HETEROARYL-IMIDAZO[L,2- A] PYRIDINES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2014-12-03 | — | — | EP | disclosed |