Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 4/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.47 |
| ▸ | LATS1 | O95835 | 1/20 | 0.36 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14875554 | 0.80 | AOC1 (0.46) | AOC1AOC3CHRNB2CHRNA4KDM4E | |
| SCHEMBL6035134 | 0.78 | AOC1 (0.59) | AOC1AOC3MAPTCHRNB2CHRNA4 | |
| SCHEMBL14204991 | 0.77 | CHRM2 (0.46) | MAPTKMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL294034 | 0.75 | AOC1 (0.55) | AOC1AOC3MAPTKMT2ACYP2E1 | |
| SCHEMBL18137970 | 0.74 | ALDH1A1 (0.50) | LATS1LATS2KMT2ACYP2D6CYP2C9 | |
| SCHEMBL5744881 | 0.73 | AOC1 (0.53) | AOC1AOC3MAPTKMT2ACYP2E1 | |
| SCHEMBL5750088 | 0.73 | AOC1 (0.53) | AOC1AOC3MAPTKMT2ACYP2E1 | |
| SCHEMBL5749554 | 0.73 | AOC1 (0.53) | AOC1AOC3MAPTKMT2ACYP2E1 | |
| SCHEMBL5748797 | 0.73 | — | — | |
| SCHEMBL30210557 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150574-B2 | Enzyme inhibitor compounds | PROXIMAGEN LIMITED (GB) | 2015-10-06 | — | — | US | disclosed |
| US-9150574-B2 | Enzyme inhibitor compounds | PROXIMAGEN LIMITED (GB) | 2015-10-06 | — | — | US | disclosed |
| US-20140357623-A1 | NEW ENZYME INHIBITOR COMPOUNDS | PROXIMAGEN LIMITED (GB) | 2014-12-04 | — | — | US | disclosed |
| US-20140357623-A1 | NEW ENZYME INHIBITOR COMPOUNDS | PROXIMAGEN LIMITED (GB) | 2014-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357623-A1 | NEW ENZYME INHIBITOR COMPOUNDS | CPN1, CTSC, DPEP1 | AOC1 184/4885AOC3 393/4885LATS1 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.