Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.63 |
| ▸ | MMP2 | P08253 | 10/20 | 0.63 |
| ▸ | MMP9 | P14780 | 10/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | ARG1 | P05089 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28052720 | 1.00 | MMP1 (0.63) | MMP1MMP2MMP9KDM4EPOLB | |
| SCHEMBL28052575 | 0.90 | MMP1 (0.65) | MMP1MMP2MMP9KDM4EPOLB | |
| SCHEMBL16274512 | 0.86 | L3MBTL1 (0.61) | MMP1MMP2MMP9KDM4EPOLB | |
| SCHEMBL28052692 | 0.85 | ALDH1A1 (0.63) | MMP1MMP2MMP9KDM4EPOLB | |
| SCHEMBL28052691 | 0.85 | ALDH1A1 (0.63) | MMP1MMP2MMP9KDM4EPOLB | |
| SCHEMBL28052580 | 0.83 | MMP1 (0.67) | MMP1MMP2MMP9POLBPTPN1 | |
| SCHEMBL11704382 | 0.79 | ALDH1A1 (0.63) | MMP1MMP2MMP9KDM4EPOLB | |
| SCHEMBL11704385 | 0.79 | ALDH1A1 (0.63) | MMP1MMP2MMP9KDM4EPOLB | |
| SCHEMBL25214104 | 0.79 | MAPT (0.75) | MMP1MMP2MMP9KDM4EPOLB | |
| SCHEMBL30384507 | 0.79 | MAPT (0.75) | MMP1MMP2MMP9KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461591-A | Cinnamoyl hydrazide compound and preparation and application thereof | UNIV LANZHOU | 2016-04-06 | — | — | CN | disclosed |
| US-9255071-B2 | Compounds having antibacterial activity, process for their preparation and pharmaceutical compositions comprising them | CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TÉCNICAS (CONICET) (AR) | 2016-02-09 | — | — | US | disclosed |
| US-20140357678-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET) (AR) | 2014-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357678-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | C5, CBR3, C1R | MMP1 3041/4885MMP2 1470/4885MMP9 2521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.