SCHEMBL16273620

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16911022	0.89	CXCR2 (0.34)	CXCR2BRD4ALDH1A1KDM4EHPGD
	SCHEMBL17600282	0.89	KDM4E (0.34)	PRKDCALDH1A1KDM4EHPGDMAPK1
	SCHEMBL16273640	0.87	MRGPRX4 (0.34)	CXCR2ALDH1A1KDM4EHPGDMAPK1
	SCHEMBL17600071	0.87	PTGER1 (0.35)	PRKDCALDH1A1KDM4EHPGDKMT2A
	SCHEMBL16273656	0.87	KDM4E (0.33)	BRD4ALDH1A1KDM4EHPGDKMT2A
	SCHEMBL17600113	0.86	KDM4E (0.34)	PRKDCALDH1A1KDM4EHPGDKMT2A
	SCHEMBL16273616	0.85	PRKDC (0.34)	CXCR2PRKDCBRD4ALDH1A1KDM4E
	SCHEMBL17600134	0.85	KDM4E (0.33)	ALDH1A1KDM4EHPGDMAPK1KMT2A
	SCHEMBL16273737	0.84	HPGD (0.36)	ALDH1A1KDM4EHPGDKMT2AMEN1
	SCHEMBL16273750	0.83	SMN1; SMN2 (0.34)	ALDH1A1KDM4EHPGDKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.