Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17616656 | 0.86 | FOLH1 (0.59) | FOLH1ALDH1A1MRGPRX4TP53HTT | |
| SCHEMBL9131892 | 0.85 | ALDH1A1 (0.77) | FOLH1ALDH1A1MRGPRX4TP53HTT | |
| SCHEMBL16273659 | 0.83 | MRGPRX4 (0.59) | FOLH1ALDH1A1MRGPRX4TP53HTT | |
| SCHEMBL16273719 | 0.83 | MRGPRX4 (0.80) | FOLH1ALDH1A1MRGPRX4TP53HTT | |
| SCHEMBL17804521 | 0.83 | MRGPRX4 (0.59) | FOLH1ALDH1A1MRGPRX4TP53HTT | |
| SCHEMBL16273649 | 0.80 | MRGPRX4 (0.55) | FOLH1ALDH1A1MRGPRX4TP53HTT | |
| SCHEMBL18831623 | 0.79 | SLC22A12 (0.45) | FOLH1ALDH1A1MRGPRX4MEN1LMNA | |
| SCHEMBL16273709 | 0.78 | F2 (0.40) | FOLH1ALDH1A1HTTMEN1LMNA | |
| SCHEMBL9561905 | 0.77 | ALDH1A1 (0.64) | FOLH1ALDH1A1MRGPRX4TP53HTT | |
| SCHEMBL528926 | 0.77 | RAB9A (0.61) | FOLH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-A1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | Sumitomo Chemical Company Limited (JP) | 2016-04-13 | — | — | EP | disclosed |
| WO-2015016373-A1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | 住友化学株式会社 (JP) | 2015-02-05 | — | — | WO | disclosed |
| WO-2014192953-A1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | 住友化学株式会社 (JP) | 2014-12-04 | — | — | WO | disclosed |