SCHEMBL16273659

SCHEMBL16273659

CCc1cc(O)ccc1OCc1ccccc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 6/20 0.59
FOLH1 Q04609 2/20 0.58
TP53 P04637 1/20 0.57
HTT P42858 1/20 0.57
CLCN2 P51788 2/20 0.52
ALDH1A1 P00352 2/20 0.50
KDM4E B2RXH2 1/20 0.44
HSD17B10 Q99714 1/20 0.44
LMNA P02545 1/20 0.44
CYP2C9 P11712 1/20 0.44
HIF1A Q16665 1/20 0.44
ELANE P08246 3/20 0.43
F2 P00734 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17616608 0.87 MRGPRX4 (0.58) MRGPRX4FOLH1TP53HTTCLCN2
SCHEMBL17804521 0.86 MRGPRX4 (0.59) MRGPRX4FOLH1TP53HTTCLCN2
SCHEMBL16273660 0.83 FOLH1 (0.61) MRGPRX4FOLH1TP53HTTCLCN2
SCHEMBL16273719 0.83 MRGPRX4 (0.80) MRGPRX4FOLH1TP53HTTCLCN2
SCHEMBL19987598 0.81 CDK4 (0.48) ALDH1A1KDM4EELANEF2
SCHEMBL1894477 0.80 ELANE (0.58) TP53ALDH1A1KDM4ELMNACYP2C9
SCHEMBL16273649 0.80 MRGPRX4 (0.55) MRGPRX4FOLH1TP53HTTCLCN2
SCHEMBL16273699 0.79 KMT2A (0.40) ALDH1A1KDM4EELANEF2
SCHEMBL21318003 0.79 MRGPRX4 (0.69) MRGPRX4FOLH1TP53HTTCLCN2
SCHEMBL8676059 0.79 PTGER1 (0.57) MRGPRX4FOLH1TP53HTTCLCN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029030-B1 TETRAZOLINONE COMPOUND, AND USE THEREFOR SUMITOMO CHEMICAL CO (JP) 2019-09-04 EP disclosed
EP-3006440-B1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME SUMITOMO CHEMICAL CO (JP) 2018-03-21 EP disclosed
US-9675072-B2 Tetrazolinone compound and application of same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-13 US disclosed
WO-2015016373-A1 TETRAZOLINONE COMPOUND, AND USE THEREFOR 住友化学株式会社 (JP) 2015-02-05 WO disclosed
WO-2014192953-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME 住友化学株式会社 (JP) 2014-12-04 WO disclosed