Sugi Predict

Sugi Predict / Compounds / SCHEMBL16273669

SCHEMBL16273669

SCHEMBL16273669

Cc1cc(-c2nn(C)c(Cl)c2C=O)ccc1OCc1ccccc1-n1nnn(C)c1=O

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 1/20 0.32
▸ FFAR4 Q5NUL3 1/20 0.32
▸ HPGD P15428 3/20 0.32
▸ MEN1 O00255 3/20 0.32
▸ CYP1A2 P05177 3/20 0.32
▸ KMT2A Q03164 3/20 0.32
▸ KDM4E B2RXH2 2/20 0.32
▸ CYP2C19 P33261 2/20 0.32
▸ MAPT P10636 1/20 0.32
▸ RXFP1 Q9HBX9 1/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ CYP3A4 P08684 2/20 0.32
▸ CYP2C9 P11712 2/20 0.32
▸ PTGER1 P34995 2/20 0.31
▸ ACLY P53396 1/20 0.31
▸ MRGPRX4 Q96LA9 1/20 0.31
▸ HTT P42858 3/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ CD274 Q9NZQ7 1/20 0.31
▸ BRD4 O60885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16273662 0.89 HPGD (0.36) HPGDMEN1CYP1A2KMT2AKDM4E
SCHEMBL17600113 0.89 KDM4E (0.34) HPGDMEN1CYP1A2KMT2AKDM4E
SCHEMBL16910994 0.89 NR1H4 (0.32) HPGDMEN1CYP1A2KMT2AKDM4E
SCHEMBL16273663 0.87 MAPT (0.36) HPGDMEN1CYP1A2KMT2AKDM4E
SCHEMBL16273637 0.86 FFAR1 (0.34) FFAR1FFAR4HPGDMEN1CYP1A2
SCHEMBL16273656 0.83 KDM4E (0.33) FFAR1FFAR4HPGDMEN1CYP1A2
SCHEMBL19987549 0.82 HPGD (0.35) FFAR1FFAR4HPGDMEN1CYP1A2
SCHEMBL16273642 0.81 HPGD (0.35) HPGDMEN1CYP1A2KMT2AKDM4E
SCHEMBL17600282 0.81 KDM4E (0.34) HPGDMEN1CYP1A2KMT2AKDM4E
SCHEMBL16273737 0.81 HPGD (0.36) HPGDMEN1CYP1A2KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3006440-B1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME SUMITOMO CHEMICAL CO (JP) 2018-03-21 — — EP disclosed
US-9675072-B2 Tetrazolinone compound and application of same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-13 — — US disclosed
US-9675072-B2 Tetrazolinone compound and application of same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-13 — — US disclosed
US-9675072-B2 Tetrazolinone compound and application of same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-13 — — US disclosed
EP-3006440-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME Sumitomo Chemical Company Limited (JP) 2016-04-13 — — EP disclosed
US-20160081340-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-24 — — US disclosed
US-20160081340-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-24 — — US disclosed
US-20160081340-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-24 — — US disclosed
WO-2014192953-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME 住友化学株式会社 (JP) 2014-12-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160081340-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME CYP2E1, MT-CO2, CASP3 FFAR1 1556/4885FFAR4 2020/4885HPGD 4259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.