Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18831221 | 0.89 | MRGPRX4 (0.33) | HPGDMRGPRX4CD274P2RX3PSD | |
| SCHEMBL16273684 | 0.89 | MRGPRX4 (0.38) | HPGDMRGPRX4CD274S1PR1S1PR5 | |
| SCHEMBL17600282 | 0.88 | KDM4E (0.34) | HPGDMRGPRX4CD274MMP1MMP9 | |
| SCHEMBL16273737 | 0.88 | HPGD (0.36) | HPGDMRGPRX4CD274P2RX3PSD | |
| SCHEMBL16273642 | 0.88 | HPGD (0.35) | HPGDMRGPRX4CD274MMP1MMP9 | |
| SCHEMBL16273667 | 0.88 | MRGPRX4 (0.35) | HPGDMRGPRX4CD274S1PR1S1PR5 | |
| SCHEMBL16273688 | 0.88 | MRGPRX4 (0.35) | HPGDMRGPRX4CD274S1PR1S1PR5 | |
| SCHEMBL16273616 | 0.86 | PRKDC (0.34) | HPGDMRGPRX4CD274FFAR4KDM4E | |
| SCHEMBL16273679 | 0.86 | HPGD (0.36) | HPGDMRGPRX4CD274P2RX3PSD | |
| SCHEMBL16273664 | 0.86 | HPGD (0.36) | HPGDMRGPRX4CD274P2RX3PSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |