Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17600283 | 0.85 | MRGPRX4 (0.33) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL16385361 | 0.83 | L3MBTL1 (0.37) | S1PR1S1PR5MAPTL3MBTL1HPGD | |
| SCHEMBL16385190 | 0.82 | P2RX7 (0.38) | S1PR1S1PR5MAPTL3MBTL1HPGD | |
| SCHEMBL16384947 | 0.81 | MRGPRX4 (0.36) | S1PR1S1PR5MAPTL3MBTL1HPGD | |
| SCHEMBL16385110 | 0.80 | MRGPRX4 (0.35) | S1PR1S1PR5MAPTL3MBTL1HPGD | |
| SCHEMBL16385533 | 0.78 | CTSS (0.42) | MRGPRX4 | |
| SCHEMBL16385379 | 0.77 | MAPT (0.34) | S1PR1S1PR5MAPTL3MBTL1HPGD | |
| SCHEMBL16911198 | 0.75 | MRGPRX4 (0.32) | PDE4APDE4BPDE4CPDE4DMRGPRX4 | |
| SCHEMBL16273636 | 0.74 | MRGPRX4 (0.34) | S1PR1S1PR5MAPTL3MBTL1PTGER1 | |
| SCHEMBL16273740 | 0.73 | CD274 (0.33) | S1PR1S1PR5MAPTHPGDPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014192953-A1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | 住友化学株式会社 (JP) | 2014-12-04 | — | — | WO | disclosed |