Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17616609 | 0.85 | NPC1 (0.57) | RAB9ANPC1KMT2AMAOBCCR5 | |
| SCHEMBL16273710 | 0.85 | NPC1 (0.54) | RAB9ANPC1KMT2AMAOBCCR5 | |
| SCHEMBL16273690 | 0.84 | MAOB (0.52) | RAB9ANPC1KMT2AMAOBCCR5 | |
| SCHEMBL16273698 | 0.84 | MAOB (0.52) | RAB9ANPC1KMT2AMAOBCCR5 | |
| SCHEMBL16273691 | 0.84 | CCR5 (0.54) | RAB9ANPC1KMT2AMAOBCCR5 | |
| SCHEMBL18831596 | 0.84 | MRGPRX4 (0.43) | RAB9ANPC1KMT2AMRGPRX4ALDH1A1 | |
| SCHEMBL18831605 | 0.83 | ALDH1A1 (0.43) | RAB9ANPC1KMT2AMRGPRX4ALDH1A1 | |
| SCHEMBL16273707 | 0.82 | RAB9A (0.51) | RAB9ANPC1KMT2AMAOBCCR5 | |
| SCHEMBL17616612 | 0.81 | NPC1 (0.55) | RAB9ANPC1KMT2AMAOBCCR5 | |
| SCHEMBL16273700 | 0.81 | ATM (0.48) | RAB9ANPC1KMT2AMAOBCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9675072-B2 | Tetrazolinone compound and application of same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-06-13 | — | — | US | disclosed |
| EP-3029030-A1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | Sumitomo Chemical Company, Limited (JP) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015016373-A1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | 住友化学株式会社 (JP) | 2015-02-05 | — | — | WO | disclosed |
| WO-2014192953-A1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | 住友化学株式会社 (JP) | 2014-12-04 | — | — | WO | disclosed |