Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 1.00 |
| ▸ | DRD1 | P21728 | 1/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 1.00 |
| ▸ | PDE4A | P27815 | 1/20 | 1.00 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | KCNMB4 | Q86W47 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | TSLP | Q969D9 | 1/20 | 0.36 |
| ▸ | SHH | Q15465 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | NECTIN4 | Q96NY8 | 2/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Daptomycin SCHEMBL17253124 | 1.00 | CTSL (1.00) | CTSLDRD1PTGS1PDE4AF2 | |
| Daptomycin SCHEMBL28102 | 1.00 | CTSL (1.00) | CTSLDRD1PTGS1PDE4AF2 | |
| Daptomycin SCHEMBL28103 | 1.00 | CTSL (1.00) | CTSLDRD1PTGS1PDE4AF2 | |
| Daptomycin SCHEMBL13491700 | 1.00 | CTSL (1.00) | CTSLDRD1PTGS1PDE4AF2 | |
| Daptomycin SCHEMBL8221760 | 1.00 | CTSL (1.00) | CTSLDRD1PTGS1PDE4AF2 | |
| Daptomycin SCHEMBL8227262 | 1.00 | CTSL (1.00) | CTSLDRD1PTGS1PDE4AF2 | |
| Daptomycin SCHEMBL23046993 | 1.00 | CTSL (1.00) | CTSLDRD1PTGS1PDE4AF2 | |
| Daptomycin SCHEMBL17351683 | 1.00 | CTSL (1.00) | CTSLDRD1PTGS1PDE4AF2 | |
| Daptomycin SCHEMBL2724847 | 1.00 | CTSL (1.00) | CTSLDRD1PTGS1PDE4AF2 | |
| Daptomycin SCHEMBL21402170 | 1.00 | CTSL (1.00) | CTSLDRD1PTGS1PDE4AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004161-B1 | ANTI-WALL TEICHOIC ANTIBODIES AND CONJUGATES | GENENTECH INC (US) | 2019-10-02 | — | — | EP | disclosed |
| US-20180085470-A1 | ANTI-WALL TEICHOIC ANTIBODIES AND CONJUGATES | GENENTECH, INC. (US) | 2018-03-29 | — | — | US | disclosed |
| US-9884126-B2 | Anti-wall teichoic antibodies and conjugates | GENENTECH, INC. (US) | 2018-02-06 | — | — | US | disclosed |
| US-20150366985-A1 | ANTI-WALL TEICHOIC ANTIBODIES AND CONJUGATES | GENENTECH, INC. (US) | 2015-12-24 | — | — | US | disclosed |
| WO-2014193722-A1 | ANTI-WALL TEICHOIC ANTIBODIES AND CONJUGATES | GENENTECH, INC. (US) | 2014-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366985-A1 | ANTI-WALL TEICHOIC ANTIBODIES AND CONJUGATES | STT3A, STT3B, DDOST | CTSL 2518/4885DRD1 3783/4885PTGS1 3631/4885 |
| US-20180085470-A1 | ANTI-WALL TEICHOIC ANTIBODIES AND CONJUGATES | STT3A, STT3B, DDOST | CTSL 3208/4885DRD1 3379/4885PTGS1 3446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.