SCHEMBL1627415

SCHEMBL1627415

O=C1CC(=O)C2CCCC12

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12444789 0.93 CA1 (0.38) CA1CA2CA4KMT2A
SCHEMBL424899 0.86
SCHEMBL8898871 0.77 TRIM24 (0.38) CA1CA2CA4KMT2A
SCHEMBL23048936 0.75 CA1 (0.31) CA1CA2CA4KMT2A
SCHEMBL4374227 0.73 MT-CO2 (0.46) CA1CA2CA4KMT2A
SCHEMBL10719777 0.73 MT-CO2 (0.46) CA1CA2CA4KMT2A
SCHEMBL3277309 0.73 CA1 (0.43) CA1CA2CA4KMT2A
SCHEMBL6535460 0.73 MT-CO2 (0.46) CA1CA2CA4KMT2A
SCHEMBL431589 0.72
SCHEMBL20663434 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9246187-B2 Non-aqueous electrolyte for lithium-ion battery UCHICAGO ARGONNE, LLC (US) 2016-01-26 US disclosed
US-9218915-B2 Non-aqueous electrolyte for lithium-ion battery UCHICAGO ARGONNE, LLC (US) 2015-12-22 US disclosed
US-8952179-B2 Synthesis process, and crystalline form of 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy} benzamide hydrochloride and pharmaceutical compositions containing it LES LABORATORIES SERVIER (FR) 2015-02-10 US disclosed
US-20140272607-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM-ION BATTERY UCHICAGO ARGONNE LLC (US) 2014-09-18 US disclosed
US-20140186721-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM-ION BATTERY UCHICAGO ARGONNE, LLC (US) 2014-07-03 US disclosed
US-20140155453-A1 SYNTHESIS PROCESS, AND CRYSTALLINE FORM OF 4-{3[CIS-HEXAHYDROCYCLOPENT A[CjPYRROL-2( 1 H)-YLjPROPOXYj BENZAMI DE HYDROCHLORI DE AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT LES LABORATOIRES SERVIER (FR) 2014-06-05 US disclosed
US-8664408-B2 Synthesis process, and crystalline form of 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]proxy}benzamide hydrochloride and pharmaceutical compositions containing it LES LABORATOIRES SERVIER (FR) 2014-03-04 US disclosed
US-20120316214-A1 SYNTHESIS PROCESS, AND CRYSTALLINE FORM OF 4-BENZAMIDE HYDROCHLORIDE AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT LES LABORATOIRES SERVIER (FR) 2012-12-13 US disclosed
US-20120088160-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM-ION BATTERY UCHICAGO ARGONNE, LLC 2012-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088160-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM-ION BATTERY VDAC1, VDAC2, CA2 CA1 11/4885CA2 3/4885CA4 45/4885
US-20140155453-A1 SYNTHESIS PROCESS, AND CRYSTALLINE FORM OF 4-{3[CIS-HEXAHYDROCYCLOPENT A[CjPYRROL-2( 1 H)-YLjPROPOXYj BENZAMI DE HYDROCHLORI DE AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT HRH2, HRH1, HRH4 CA1 151/4885CA2 43/4885CA4 156/4885
US-20120316214-A1 SYNTHESIS PROCESS, AND CRYSTALLINE FORM OF 4-BENZAMIDE HYDROCHLORIDE AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT HRH4, HRH2, HRH1 CA1 788/4885CA2 78/4885CA4 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.