Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL16280437

Cc1c(C(F)(F)F)cnc(N)c1N.N.N

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MBOAT4 Q96T53 3/20 0.35
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NOS3 P29474 2/20 0.33
NOS2 P35228 2/20 0.33
AURKA O14965 1/20 0.33
KDR P35968 1/20 0.33
AURKB Q96GD4 1/20 0.33
NOS1 P29475 1/20 0.33
PIK3CA P42336 2/20 0.32
MAP3K12 Q12852 2/20 0.31
PIK3CD O00329 1/20 0.30
PTK2 Q05397 1/20 0.30
ASPH Q12797 1/20 0.30
MTOR P42345 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9276814 0.98 MBOAT4 (0.36) MBOAT4HPGDHSD17B10NOS3NOS2
SCHEMBL29435785 0.98 MBOAT4 (0.36) MBOAT4HPGDHSD17B10NOS3NOS2
SCHEMBL13973112 0.83 HPGD (0.36) MBOAT4HPGDHSD17B10NOS3NOS2
SCHEMBL31214202 0.83 HPGD (0.36) MBOAT4HPGDHSD17B10NOS3NOS2
SCHEMBL15862849 0.82 NOS3 (0.32) NOS3NOS2NOS1
SCHEMBL29936876 0.80 HPGD (0.34) MBOAT4HPGDHSD17B10NOS3NOS2
SCHEMBL31240982 0.78 LMNA (0.38) MBOAT4HPGDHSD17B10NOS3NOS2
SCHEMBL21606876 0.78 PIK3CD (0.36) MBOAT4HPGDHSD17B10NOS3NOS2
Hydrochloric Acid SCHEMBL27573305 0.77 PIK3CD (0.35) MBOAT4HPGDHSD17B10NOS3NOS2
SCHEMBL28490357 0.75 MBOAT4 (0.37) MBOAT4HPGDHSD17B10AURKAKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278983-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-08 US disclosed
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL NR4A1, NR2C2, NR0B1 MBOAT4 3664/4885HPGD 4230/4885HSD17B10 1343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.