Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.59 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.59 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.59 |
| ▸ | KRAS | P01116 | 10/20 | 0.59 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.48 |
| ▸ | DTYMK | P23919 | 2/20 | 0.45 |
| ▸ | FUT6 | P51993 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055236 | 1.00 | POLB (0.61) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL146916 | 0.93 | POLB (0.51) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL16280921 | 0.92 | POLB (0.71) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL13111577 | 0.92 | POLB (0.71) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL13127150 | 0.92 | POLB (0.71) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL23366177 | 0.92 | POLB (0.71) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL10055280 | 0.92 | POLB (0.71) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL16609774 | 0.90 | POLB (0.65) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL24864698 | 0.88 | POLB (0.65) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL14330855 | 0.88 | POLB (0.67) | POLBP2RY2P2RY4P2RY6KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9777320-B2 | Molecular adaptors for dye conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-9702001-B2 | Scaffold-based polymerase enzyme substrates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-8906612-B2 | Scaffold-based polymerase enzyme substrates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| WO-2012027625-A2 | SCAFFOLD-BASED POLYMERASE ENZYME SUBSTRATES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |